Vacunas para COVID-19 basadas en Adenovirus

Authors

  • Everardo González-González Universidad Autónoma de Nuevo León
  • Iván Delgado-Enciso Universidad de Colima https://orcid.org/0000-0001-9848-862X
  • Margarita de la Luz Martínez Fierro Universidad Autónoma de Zacatecas
  • Rebeca Hodgers-Gonzalez Alfa Medical Center
  • Giacomo Maggiolino-Tuyu Alfa Medical Center https://orcid.org/0009-0009-3431-8678
  • Thomas Joseph Hodgers-Fernandez Alfa Medical Center
  • Iram Pablo Rodríguez-Sánchez Universidad Autónoma de Nuevo León https://orcid.org/0000-0002-5988-4168

DOI:

https://doi.org/10.29105/bys7.13-109

Keywords:

COVID-19, SARS-CoV-2, vaccine, pandemic, adenovirus, viral vector

Abstract

The COVID-19 pandemic has highly impacted the world, both negatively and positively. On the positive side, we can highlight the outstanding effort that has been made by pharmaceutical companies, governments and schools around the world. This with the intention of responding to this disease with the development of tools for the diagnosis and treatment of COVID-19. An example to mention is the creation of vaccines based on viral vectors, vaccines that have been in the study phase for some time but that the pandemic has accelerated their application in humans. This disease has brought a great advance in health technology, being able to apply the knowledge of years of gene editing to agents such as viruses so that they can be used as vaccines for COVID-19.

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Author Biographies

Everardo González-González, Universidad Autónoma de Nuevo León

Maestro y doctor en biotecnología por el ITEMS, miembro del Sistema Nacional de Investigadores 1. Profesor de la FCB de la UANL.

Iván Delgado-Enciso, Universidad de Colima

Profesor titular de la Facultad de Medicina de la Universidad de Colima, México. Jefe del Departamento de Investigación del Instituto Estatal de Cancerología de los Servicios de Salud del Estado de Colima, México. Especialista en Biología Molecular e Ingeniería Genética. Miembro del Sistema Nacional de Investigadores nivel 3.

Margarita de la Luz Martínez Fierro, Universidad Autónoma de Zacatecas

Doctora en Ciencias con Orientación en Biología Molecular e Ingeniería Genética; miembro de la Academia Mexicana de Ciencias y del Sistema Nacional de Investigadores Nivel 3. Líneas de investigación: Medicina y Epidemiología Molecular de enfermedades humanas y Tecnologías para la salud.

Rebeca Hodgers-Gonzalez, Alfa Medical Center

The COVID-19 pandemic has highly impacted the world, both negatively and positively. On the positive side, we can highlight the outstanding effort that has been made by pharmaceutical companies, governments and schools around the world. This with the intention of responding to this disease with the development of tools for the diagnosis and treatment of COVID-19. An example to mention is the creation of vaccines based on viral vectors, vaccines that have been in the study phase for some time but that the pandemic has accelerated their application in humans. This disease has brought a great advance in health technology, being able to apply the knowledge of years of gene editing to agents such as viruses so that they can be used as vaccines for COVID-19.

Giacomo Maggiolino-Tuyu, Alfa Medical Center

Estudiante Prepa Tec Campus Santa Catarina, Bachillerato Internacional. A realizado Summer at Hopkins 2022, Miembro del Gobierno Estudiantil gestión 2023-2024, Grupo Estudiantil Global Leaders 2022-2023.

Thomas Joseph Hodgers-Fernandez, Alfa Medical Center

Médico Cirujano y Partero, Especialista en Radiología e Imagen, certificado por Consejo Mexicano de Radiología e Imagen y Miembro del Colegio de Radiólogos de Nuevo León AC. Sub Director del Alfa Medical Center, Ave. Benito Juárez #314 pte Col. Centro, Guadalupe, Nuevo León CP 67100.

Iram Pablo Rodríguez-Sánchez, Universidad Autónoma de Nuevo León

Doctor en Ciencias, jefe del Laboratorio de Fisiología Molecular y Estructural, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León. Miembro del Sistema Nacional de Investigadores nivel 2.

References

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Ikegame S, Siddiquey MNA, Hung CT, Haas G, Brambilla L, Oguntuyo KY. 2021. Neutralizing activity of Sputnik V vaccine sera against SARS-CoV-2 variants. Nature Communications. 12(1):1–11. DOI: https://doi.org/10.1038/s41467-021-24909-9

Knoll MD y Wonodi C. 2021. Oxford–AstraZeneca COVID-19 vaccine efficacy. The Lancet. 397(10269):72–4. DOI: https://doi.org/10.1016/S0140-6736(20)32623-4

Muñoz-Valle JF, Sánchez-Zuno GA, Matuz-Flores MG, Hernández-Ramírez CO, Díaz-Pérez SA, Baños-Hernández CJ. 2022 Efficacy and Safety of Heterologous Booster Vaccination after Ad5-nCoV (CanSino Biologics) Vaccine: A Preliminary Descriptive Study. Vaccines. 10(3):400. DOI: https://doi.org/10.3390/vaccines10030400

Sharma A y Worgall S. 2016. Adenoviral Vectors Vaccine: Capsid Incorporation of Antigen. Adenoviral Vectors for Gene Therapy: Second Edition. 6;571–90. DOI: https://doi.org/10.1016/B978-0-12-800276-6.00022-X

Self WH, Tenforde MW, Rhoads JP, Gaglani M, Ginde AA, Douin DJ. 2021. Comparative Effectiveness of Moderna, Pfizer-BioNTech, and Janssen (Johnson & Johnson) Vaccines in Preventing COVID-19 Hospitalizations Among Adults Without Immunocompromising Conditions — United States. Morbidity and Mortality Weekly Report. 70(38):1337. DOI: https://doi.org/10.15585/mmwr.mm7038e1

Published

2024-01-02

How to Cite

González-González, E., Delgado-Enciso, I., Martínez Fierro, M. de la L., Hodgers-Gonzalez, R., Maggiolino-Tuyu, G., Hodgers-Fernandez, T. J., & Rodríguez-Sánchez, I. P. (2024). Vacunas para COVID-19 basadas en Adenovirus. Biología Y Sociedad, 7(13), 82–87. https://doi.org/10.29105/bys7.13-109

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